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IRI caused activation of the IGF1R ( p = 0.0122)/PI3K ( p = 0.0022) signalling, as compared to the aerobic control group

Supplementary Data 13 (download XLSX Source data for Supplementary Fig

Shih AY, Li P, Murphy TH (2005) A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo

However, the conversion of folic acid to active forms of folate is relatively slow in human cells ( Inter-individual variability in homocysteine, due to genetically determined metabolic heterogeneity, will likely become a fruitful area of research