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Gently squeeze the pipettes bulb before inserting the pipette tip into the bacteriostatic water

Additionally, evidence supports the involvement of oxidative damage in demyelinization and pathogenesis of MS lesions, acting in cooperation with nitric oxide(NO) radicals [113]

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As shown in Table 1 , inhibitors or antagonists of these targets have shown good results in animals, such as CXCR3, CXCR4, CXCL10, CXCL12, and CXCL13, especially the antibody of CXCL10 (MDX-1100) has entered clinical trials ( ( Figure 2 )