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5 Jiangsu Provincial Key Laboratory of Critical Care Medicine, Nanjing 210009, Peoples Republic of China Correspondence: Ruihua Shi Department of Gastroenterology, Zhongda Hospital Affiliated to Southeast University, Nanjing 210009, Peoples Republic of China Tel +86 25 83262833 Fax +86 25 83262830 Email [email protected] Guoqiu Wu Center of Clinical Laboratory Medicine, Zhongda Hospital, Southeast University, Nanjing 210009, Peoples Republic of China Tel +86-25 83272150 Email [email protected] Aim: Although Clopidogrel is safe in healthy volunteers, it can induce recurrence of gastric ulcers in high-risk patients

doi: 10.1371/journal.pbio.0050177 586 DecodeME

In diet-induced obesity animal models, NNMT inhibition demonstrated metabolic changes including alterations in adipocyte lipid content without affecting food intake patterns, coupled with significant reductions in white adipose tissue mass in treated mice

TAMs are M2 macrophages that play a key role in immune evasion and are recruited into the TME by tumor-secreted VEGF [62]