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Thus, it is likely that the intake of foods and/or beverages with high levels of exogenous AGEs create more health problems than endogenously produced AGEs, although both exogenous and endogenous AGEs are similar in their biological functions and potentially act synergistically to stimulate oxidative stress, inflammation, and cellular damage, contributing to detrimental pathophysiology 2,3,4,24
Neuroimaging findings and clinical evaluation were critical in establishing the diagnosis
Phygene, Fuzhou, China), which can readily enter cells and be cleaved by esterase to yield DCFH, a polar, nonfluorescent product