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Disruption of glycosylation or glycan structure is also associated with disease and critical illness [4, 34]

Increased tear osmolarity in dry eye disease has been found to stimulate production of inflammatory cytokines and matrix metalloproteinases by ocular surface epithelial cells [155]

(2013) showed that the administration of cocaine to male rats resulted in an increased level of brain-derived neurotrophic factor protein (BDNF) in the prefrontal cortex of their sons

In patients with T2DM who do not have atherosclerotic cardiovascular disease (ASCVD)/indicators of high-risk, HF, or CKD and who need to minimize hypoglycemia and/or promote weight loss, GLP-1 RAs are generally recommended as a second or third-line option as add-on to metformin therapy