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From the stomach to the pancreas, small intestine, liver and colon, vitamin C plays a role in the pathophysiology of many common disorders encountered by gastroenterologists

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These same complexes are also capable of modifying non-genomic activities by altering signal transduction or introducing post translational modifications yielding epigenome reprogramming

His experiments demonstrated that injections of extracts from Langerhans islets (figure 3) helped to reduce glycosuria (the excretion of glucose into urine) and diabetic symptoms in pancreatectomised dogs (Vecchio, Tornali, Bragazzi )