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Roshdy E, Rajaratnam V, Maitra S, et al

However, the presence of ulcers, bleeding, and an imbalance in the mucosal environment can further compromise the integrity of the intestinal mucosal barrier, ultimately resulting in a detrimental cycle of ongoing mucosal damage and destruction, impaired reconstruction capacity, and exacerbated homeostatic imbalance (Chang et al., 2013)

Indeed, estimates of the probability of recurrence of depression are as high as 60% by 1 year (Naicker et al., 2013)

Similarly, the genetic inactivation or small-molecule-mediated inhibition or degradation of GPX4 leads to ferroptosis in multiple cell types