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Notably, previous studies have revealed that transgenic overexpression of 6-PFKFB3 in mice results in notable cardiac damage, characterized by changes in heart weight-to-body weight ratio, cardiomyocyte length and increased cardiac fibrosis (51,53)

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This study describes the trends in decompensated cirrhosis among Medicare beneficiaries in the United States (US), with a focus on the prevalence of OHE and related hospitalizations and medication use