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doi: 10.7150/ijbs.15811

How does dihexa nasal spray work at the molecular level? Dihexa binds to c-Met receptors on neuronal membranes and amplifies signaling from hepatocyte growth factor (HGF), activating downstream pathways including PI3K/Akt and MAPK/ERK that promote dendritic spine formation and synaptic remodeling in hippocampal neurons

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