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Different ion channels and transporters at the BBB can complete the transmembrane transmission of charges, thereby helping to maintain synaptic signaling activity and ion stability in the internal environment

C., and Bradfield, C

Hydrogels are a promising class of biomaterials produced by natural and synthetic polymers with high water content, high porosity, and mechanical properties like those of native tissue [22,23,24]

IFN-loaded chitosan-cyclodextrin NPs reduced inflammation, demyelination, activation of microglia and astrocytes and the expression of co-stimulatory proteins on CD11b + cells which eventually alleviated the EAE symptoms [82]