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2a, b) suggested dysfunctional CD8 + T C glucose metabolism as a hallmark of SARS-CoV-2 infection

Mild intensity physical exercise has been found to increase gas clearance and reduce bloating.[45] Women who are more physically active tend to have fewer and less-severe IBS symptoms.[46] One small randomized controlled trial (RCT) showed that increasing physical activity had symptomatic benefits in those with constipation-predominant IBS.[47] Regular exercise helps reduce symptoms of gastroesophageal reflux disease, but vigorous exercise may worsen symptoms.[48] Despite these demonstrated benefits of exercise on GI symptoms, research does not support alternative exercise recommendations for those with IBS versus the general population

10.1111/cts.13250

Schiff RD, Mertelsmann R, Andreeff M , Berman E, Gee TS, Kempin SJ, Berenson S, in transformation CBLDCIR, Proc ASCO PRL