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Research design & analyst oversight At GMI, our research methodology is built on a foundation of human expertise, rigorous validation, and complete transparency

Quality of included reports was scored using the Jadad composite scale,13 which assesses the description of randomization, blinding, and withdrawals in the reports.14 The quality scale ranges from 0 to 5 points with a low quality report of score 2 or less and a high quality report of score at least 3.15 All discrepancies were resolved after going back to the original source papers, by consensus and involvement of a third reviewer when necessary