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doi: 10.1016/j.biomaterials.2018.01.018

Human evidence to date suggests NAD+ precursors appear to be safe: Decades of research on NR and other NAD+ precursors have not shown increased cancer risk or major safety concerns in humans, though research is ongoing

You can get that resilience back

For example, phage OMKO1 infects PsA and selects for evolved phage resistance that coincides with reduced multidrug efflux (Mex) pump function to achieve reduced antibiotic resistance 9 , a trade-off previously exploited in a clinical case of phage therapy 10