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Free Radic Biol Med (2019) 136:17282

Patients received a median of 6 cycles of induction chemotherapy in combination with trastuzumab, with or without pertuzumab, prior to study entry

Ferroptosis is a form of cell death driven by the accumulation of iron-dependent lipid peroxides, and it differs from traditional forms of cell death such as apoptosis and necrosis ( In lung cancer, the expression profiles of GPX4 (glutathione peroxidase 4) and SLC7A11 (solute carrier family 7 member 11) are closely associated with patient prognosis