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doi:10.4103/ijt.ijt 120 24

Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging

112 DAN encompasses multiple subtypes, including cardiovascular autonomic neuropathy (CAN), gastrointestinal autonomic neuropathy, genitourinary autonomic neuropathy, sudomotor dysfunction, hypoglycemia unawareness, and pupillary dysfunction, each affecting different organ systems and presenting a spectrum of clinical manifestations