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Periodontal bacteria stimulate immune cells to release MMP8 into the bloodstream, and studies have shown that serum MMP8 levels are higher in patients with generalized and invasive periodontitis (Nizam et al., 2014)

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How Creatine Raises Creatinine Without Kidney Harm Creatine is phosphorylated in muscle to phosphocreatine, then cyclized to creatinine at a steady rate of roughly 1.7% of total creatine stores per day