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Here are some other ways to help increase levels of glutathione, along with taking care to optimize vitamin D: limit alcohol consumption, avoid smoking cigarettes decrease exposure to POPs increase intake of other antioxidants to decrease overall oxidative stress increase intake of nutrients that promote glutathione production, such as NAC (N-acetylcysteine), 1000 mg/day, whey, or SAMe get enough magnesium and selenium in the diet, as both are necessary for glutathione production the natural herb milk thistle can help recycle glutathione Aerobic exercise can increase your glutathione levels

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At low concentrations (0.01 nM), MMP1 and MMP2 gene expression increases, facilitating removal of damaged ECM proteins