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An aberrant HGF/c-MET signaling can lead to uncontrolled proliferation, motility, invasiveness, and angiogenesis and can play an essential role in the development, progression and survival of cancer including head and neck squamous cell carcinoma (HNSCC) [9]

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The response curves show that most participants were still losing weight at week 68, suggesting that longer treatment durations might produce even greater reductions

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