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appears to suggest that such a trade-off indeed exists for antimalarials, particularly with therapy targeting host factors

At the epithelial interface, probiotic bacteria, including Bifidobacterium -containing formulations, can preserve tight junction organization (e.g., ZO-1/occludin/claudins) and counter increases in permeability, thereby limiting the translocation-driven inflammatory amplification that is central to radiation-induced mucosal injury 90

CC chemokines help recruit immune cells to the gonadal environment, promoting the removal of damaged cells and supporting testicular homeostasis (Zlotnik and Yoshie 2012)