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When comparing daily cumulative intake to 0 per week (reference), the hazard ratios were 2.96 (95% confidence interval, 1.26-6.97) for ischemic stroke and 2.89 (95% confidence interval, 1.18-7.07) for Alzheimer's disease

Clinically, HDAC6 inhibitors are under investigation for the treatment of neurodegenerative diseases and cancers, where restoration of MT acetylation can improve axonal transport or sensitizes tumor cells to chemotherapy [138, 139]