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Considering the established role of SUMO modification in maintaining protein stability and oncogenic activation 23,24 , these results suggest that MAT2A enhances SRF SUMOylation to stabilize SRF

Snai1 can induce partial EMT in renal tubular epithelial cells, initiate metabolic reprogramming of renal tubular epithelial cells, inhibit fatty acid metabolism, and maintain inflammation, thereby leading to RF [59, 60]

Oxidative stress plays a key role in the pathogenesis of asthma, which is why redox biomarkers could have considerable diagnostic potential in asthma ( Table 1 )

In line with this notion, the score of GMGS was significantly higher in MMRd patients, possibly indicating favorable antitumor immune responses (Figure 7E)