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In dietinduced obese mice, NNMTi treatment significantly reduced liver weight, liver volume, and hepatic triglyceride levels, alleviated hepatic steatosis and inflammatory infiltration, downregulated inflammatory factors (such as TNF and IL6) and lipogenic genes (such as FAS), and upregulated lipolytic genes (such as ATGL) in the liver

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Once reconstituted with bacteriostatic water, refrigerate at 4 C and use within approximately 28 days, bacterial growth and peptide degradation both accelerate in reconstituted solutions [13]

Nat Rev Neurosci 8 : 101113