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Am J Pathol 2003

"Your firm did not implement effective CAPA to reduce recurrence of severe contamination hazards including, but not limited to, operator error that had contributed significantly to recurring sterility and media-fill failures over the past five years," the agency added

6.2 Associating mtDNA integrity with comorbidities and disease progression Longitudinal studies are increasingly linking mtDNA integrity to the risk of developing non-AIDS-defining comorbidities, positioning mitochondrial decline as a central mechanism in HIV-associated accelerated aging