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Proc Natl Acad Sci U S A 2007;104:19345-50

14 AD induces changes in amyloid precursor protein cleavage and production of the amyloid precursor protein fragment beta-amyloid (A) along with hyperphosphorylated tau protein aggregation

Reassuringly, genes that are upregulated in HLRCC clinical samples relative to normal kidney tissues 7 are also significantly enriched with oxidative stress genes (hypergeometric P value of 3.984e06)