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Biol Psychiatry (2008) 64:71826.10.1016/j.biopsych.2008.05.014 258 ParpuraVBakerBJJerasMZorecR

Orally administered arctigenin alleviated colitis in mice by enhancing mucosal healing, primarily through accelerating colonic epithelial cell migration without affecting proliferation through the activation of the focal adhesion kinase (FAK) [496]

This interaction helps to discriminate between invasive pathogenic organisms and harmless antigens