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While human studies are ongoing, preclinical data highlight its role in reducing inflammation and promoting tissue regeneration

It has been reported that applying the ES on end-to-end coaptation of the nerves or even auto-transplantation could improve the result of nerve regeneration 26,27

Dev Cell 56:881905

Considering ROS and Ca 2+ are also core signaling modulators in various neutrophils responses, it remains an intriguing question how neutrophils prioritize downstream fates, such as phagocytosis, degranulation or releasing NETs, upon encountering the pathogens