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ZIL exists as a liquid at ambient temperature, while almost all zwitterions, including amino acids, are solids

A compromised gut barrier is both a cause and a consequence of dysbiosis, and intervening at the level of mucosal integrity, which is precisely what BPC-157 does in animal models, represents a mechanistically coherent approach to gut-mediated systemic aging

The arginine salt form of BPC-157 is generally considered to have enhanced stability in liquid form compared to the standard acetate salt

The FDA placed it on a Category 2 do-not-compound list in 2023 over impurity and immune-reaction concerns, so no licensed compounding pharmacy can prepare it either