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Gould DJ, El-Sabawi B, Goel P, Badash I, Colletti P, Patel KM

Without VIC, enzyme inactivation occurs rapidly but remains reversible [24,45]

Consequently, new combinations of cytokines such as IL-7, IL-15, and/or low doses of IL-2 are becoming more appealing in CAR-T cell manufacture strategies [59, 86, 87]