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In AD research, researchers employed methylation arrays alongside PCR-based methylation-sensitive high-resolution melting (MS-HRM) analysis to examine blood DNA from 56 patients with late-onset Alzheimers disease (LOAD) and 55 healthy controls (59)

On the other hand, certain lncRNAs function as transcriptional repressors by blocking the binding or recruitment of transcription factors and RNA polymerase to gene promoters

Interestingly, 1-week post-treatment, GFAP expression was reduced to ~49% in untreated and ~28.8% in LPC-treated slices, suggesting mitigation of the astroglial response

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