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Given our data that shows abrogation or inhibition of RABGAP1 results in less amyloidogenic processing of APP, targeting RABGAP1 could be a promising strategy for therapeutics

Lifestyle: Prioritize regular sleep, moderate exercise, and reduced alcohol/tobacco exposure.

Availability of data and materials The data that support the findings are available from the Exercise and Biochemical Nutritional Laboratory (EBNL) in the Department of Human Performance of Baylor University and the grant sponsor, being the Function Research Group of Kyowa Hakko Bio Co., Ltd