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Among several essential factors accelerating age-associated neuropathology, oxidative stress, impaired mitochondrial function, neuroinflammation, and compromised blood-brain barrier integrity are significantly modulated by sleep disruption often observed in elderly subjects (Brunetti et al., 2021

Therefore, participants were included in this study if they were aged 50 years and underwent assessment at wave 1 including measurement of plasma folate and plasma total B 12 and screening for depression

Due to its composition of phenolic compounds (e.g., phenolic acid, flavonoids, stilbenes, and tannins), vitamins (e.g., B-complex, A, D, E, and K), and minerals (e.g., potassium, phosphorus, magnesium, and zinc), S

It is frequently used as an extra-label drug in animals, and should not be employed without veterinarian advice