glutathione mitochondrial fusion

glutathione mitochondrial fusion Mitochondria in oxidative stress, inflammation and aging: from mechanisms to therapeutic advances Mitochondrial Glutathione: Regulation and Functions

Name: glutathione mitochondrial fusion Mitochondria in oxidative stress, inflammation and aging: from mechanisms to therapeutic advances Mitochondrial Glutathione: Regulation and Functions
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Mitochondrial Glutathione: Regulation and Functions Gaetano Calabrese, Bruce Morgan, Jan Riemer, 2017 The diversified role of mitochondria in ferroptosis in cancer Cell Death & Disease Mitochondrial metabolism regulates macrophage biology Journal of Biological Chemistry Altered mitochondrial fusion drives defensive glutathione synthesis in cells able to switch to glycolytic ATP production ScienceDirect

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Accordingly, inhibition of glutathione biosynthesis has been harnessed as a therapeutic strategy in various preclinical models, including KRAS-driven pancreatic cancer and non-small cell lung cancer 19,20,38