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Efficacy and safety of nivolumab plus ipilimumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib: The CheckMate 040 randomized clinical trial

Both are FDA-approved, supported by large-scale clinical trials, and have demonstrated superior results compared to older weight management medications

These results support the findings of previous trials based on pregnant women [33] and also was verified by a previous meta-analysis [34], which showed that SAMe was not significantly associated with non-serious adverse events and no serious adverse events were reported

10.1038/ng1095 111 Lariosa-WillinghamK.LeonoudakisD