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For the enzymatic hydrolysis of conjugated metabolites, the dried residues obtained from the eutylone-treated hepatocyte incubations were reconstituted in the corresponding enzyme buffer containing -glucuronidase (2000 units/mL in 50 mM potassium phosphate buffer, pH 6.8) or sulfatase (500 units/mL in 200 mM sodium acetate buffer, pH 5.0) and incubated at 37 C for 2 h

Qin et al., 2016)

This study evaluated the multiple aspects of pathogenesis, including oxidative stress, inflammatory markers, Ryanodine-receptor-two-complex oxidation, and the leakage and hyper-phosphorylation of tau protein

The essential role of P53 in hyperpigmentation of the skin via regulation of paracrine melanogenic cytokine receptor signaling