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In analyses of ChIP-seq data, we observed that many of these genes were devoid of NRF2 in their promoter regions

5a,b and Extended Data Fig

Brioukhanov, A.L., Nesatyy, V.J., and Netrusov, A.I., Biochemistry (Moscow), 2006, vol

Interestingly, hypoxia inhibits METTL14 expression in a HIF-1-dependent manner, which in turn reduces m6A methylation of the SLC7A11 mRNA 5UTR in HCC and up-regulates SLC7A11 expression via the YTHDF2 pathway to inhibit ferroptosis in HCC [101]