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termed hyFc that was constructed via nonimmunogenic, noncytolytic and flexible Fc conjugate consisting of IgD and IgG4 was applied

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doi: 10.1038/sj.ijo.0801844

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Notably, bisulfite-based PCR analysis highlighted that LINE-1 hypomethylation was associated with aggressive and advanced GC, suggesting its clinical value as a predictive GC-specific epigenetic biomarker [188]

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