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Figure 1 2.2 Patients The study cohort were twenty children treated for (11 males and 9 females), median age 10.5 years, range 614 years, who were on follow-up at the Pediatric Endocrinology Clinic at HaEmek Medical Center in 20152022 and agreed to participate the study

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Epitalon has been the subject of several anti-aging studies however, quantitative data on the biomolecular pathway leading to telomere length increase, hTERT mRNA expression, telomerase enzyme activity, and ALT activation have not been extensively studied in different cell types