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In this study, we documented the first evidence that metabolites and miRNAs can be clustered by disease severity groups and thus provide as a tool to identify potential biomarkers of clinical disease severity in AMN patients

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[DOI] [PMC free article] [PubMed] [Google Scholar] 76.Burgos J., Viribay A., Calleja-gonzlez J., Fernndez-lzaro D., Olasagasti-ibargoien J., Seco-calvo J., Mielgo-ayuso J

The E3 ligase acts as a docking platform to attach the Ub-containing E2 enzyme to a particular substrate, enabling the Ub to bind to the lysine residue of the substrate protein