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DFO and FER-1 block ARPE-19 necrobiosis from sodium iodate exposure (82)

Jamalpoor A, van Gelder CA, Yousef Yengej FA, Zaal EA, Berlingerio SP, Veys KR, Pou Casellas C, Voskuil K, Essa K, Ammerlaan CM, Rega LR, van der Welle RE, Lilien MR, Rookmaaker MB, Clevers H, Klumperman J, Levtchenko E, Berkers CR, Verhaar MC, Altelaar M, Masereeuw R, Janssen MJ (2021) Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis

They induce an immune response again st the spike protein on the viruss surface, blocking its entry into cells and providing an antiviral effect

Tte et al found that CYP4A inhibition suppresses the toxic effects of hepatocyte death on the pathological progression of steatosis under ethanol exposure and effectively alleviates AFLD progression