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Unsupervised hierarchical clustering grouped the top 50 differentially methylated CpG sites principally by sampling intervention group (placebo or supplementation) and showed a different methylation profile for each group (Fig

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The two cysteine residues (positions 7 and 14) form an intramolecular disulfide bond that constrains the molecule into a small loop, mirroring the corresponding region of native human growth hormone (residues 177191) with an N-terminal Tyr added for synthesis and labeling reasons

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