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Balsano, C., Liver-spleen axis in nonalcoholic fatty liver disease

Given the absence of long-term human trial data, conservative use under clinical supervision is the standard position among practitioners who take the evidence seriously

However, the mechanism by which NAC-mediated VWF/p38 MAPK affects pulmonary fibrosis in COPD involving the immune response and EMT is still poorly understood, highlighting a major gap in knowledge given that NAC-mediated VWF/p38 MAPK may be of significance to pulmonary fibrosis in COPD