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Oxidative dysregulation in early life stress and posttraumatic stress disorder: a comprehensive review

It could be responsible for maintaining homeostasis between DNA damage, senescence, and apoptosis under oxidative stress ( SIRT1 is redistributed at the chromatin level, causing deregulation at the transcription level and DNA damage ( SIRT-1 mRNA expression and induces apoptosis (Tinkov et al., 2021)