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Iron increases lipid deposition via oxidative stress-mediated mitochondrial dysfunction and the HIF1alpha-PPARgamma pathway

Pharmacokinetic and Pharmacodynamic Evaluation of the Novel CCR1 Antagonist CCX354 in Healthy Human Subjects: Implications for Selection of Clinical Dose

However, the long-term systemic effects of chronic NNMT inhibition on methylation pathways, liver function, and cardiovascular health have not been studied