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All three AKT isoforms can upregulate oxygen metabolism and lactate production in human hepatocellular carcinoma cell lines

For each blood sample, biochemical quantification of alkaline phosphatase, aspartate transaminase, alanine aminotransferase, urea and glucose (Table 3) was carried out to assess the potential toxicity of APAP on the organs involved in its degradation and elimination (liver, kidneys)

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The authors also gratefully acknowledge Purdue Institute for Drug Discovery (PIDD) for both high-throughput screening and programmatic grants for funds