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As these mechanisms are pertinent to the pathogenesis of AF, the putative benefits of pure resveratrol, or its derivatives with improved pharmacokinetic parameters, in AF prevention and/or treatment warrant interrogation in human clinical trials [67,68]

[5] Subirs N, Prez-Saad HM, Berlanga JA, Aldana L, Garca-Illera G, Gibson CL, Garca-Del-Barco D

Lancet 20032;372:1906-13 The number of people with obesity is increasing, and this is a significant concern because obesity is linked to various health problems such as heart disease, stroke, diabetes, respiratory issues, and cancer

Activation of HSCs is marked by upregulation of -smooth muscle actin (-SMA) (Figure 4)