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To minimize the formation of photoactive byproducts, the culture medium was replaced with Hanks Balanced Salt Solution (HBSS

Effectiveness of the iron chelator CN128 in mitigating the formation of dopamine oxidation products associated with the progression of parkinsons disease

coli (Twist Biosciences, South San Francisco, CA), also including the conservative mutation K192R to incorporate a second Bsa I cleavage site

83 In vitro, knockdown of TYK2 in murine and human MPNST cells significantly increased cell death, while knockdown in vivo led to a decreased tumour volume in a subcutaneous mouse model, supporting a role for TYK2 in driving MPNSTs