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A precursor of cysteine, known as L-2-oxothiazolidine-4-carboxylic acid (OTC), decreases neurobehavioral performance in stroke models (Liu Y

Another CD38 mAb, Isatuximab, almost completely inhibits the enzymatic activity of recombinant CD38 (5 nmol/L) at concentrations of 20~200 nmol/L, including its hydrolase activity [83]

Using synergistic drug combination prediction algorithms, such as multi-objective evolutionary algorithms and random search algorithms, synergistic drug combinations can be rapidly screened from large-scale drug combination spaces (Zinner et al., 2009)