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Description

It has been demonstrated that the missense variant NQO1, found in 4-20% of the human population, results in no detectable NQO1 activity due to rapid degradation of the NQO1 P187S protein

The canonical pathways with the top highest z-scores include White Adipose Tissue Browning Pathway (3.13), Integrin Signaling (2.82), Myelination Signaling Pathway (2.8), Ephrin Signaling Pathway (2.67), and Transcriptional Regulation by RUNX2 (2.6