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MitoCORE includes the powerful antioxidant trio of alpha lipoic acid, N-acetylcysteine and acetyl L-carnitine, all shown to recharge cellular energy production and the primary cellular antioxidant pools of glutathione and vitamins E and C

System X c , a cystine/glutamate antiporter composed of solute carrier family 7 member 11 (SLC7A11/xCT) and solute carrier family 3 member 2 (SLC3A2), mediates the import of extracellular cystine, which is subsequently reduced to cysteine for GSH synthesis ( c or GPX4 disrupts cellular redox homeostasis, leading to ROS accumulation and unchecked LPO, ultimately triggering ferroptotic cell death

Hydroxyl amino acids Serine (Ser/S) is one of three amino acids having an R-group with a hydroxyl in it (threonine and tyrosine are the others)

Polydatin ameliorates renal ischemia/reperfusion injury by decreasing apoptosis and oxidative stress through activating sonic hedgehog signaling pathway