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(2009) Mechanistic and kinetic details of catalysis of thiol-disulfide exchange by glutaredoxins and potential mechanisms of regulation

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While roGFP2 WT was completely oxidized at even very low PfGrx C32S/C88S (SSG) concentrations, 1 M PfGrx C32S/C88S (SSG) glutathionylated approximately 50% of 1 M roGFP2 C151S (SH) suggesting that the redox couples roGFP2 C151S (SSG)/roGFP2 C151S (SH) and PfGrx C32S/C88S (SSG)/PfGrx C32S/C88S (SH) have very similar redox potentials

Since most non-oxidizing biocides are both long lived and/or difficult to destroy, oxidizing biocides, which can be easily destroyed by addition of a reducing reagent to the blowdown stream, are preferred from the standpoint of minimizing the environmental impact of cooling tower blowdown or spills